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Ambien 10mg (zolpidem tartrate) requires a valid prescription from a DEA-registered US healthcare provider as a Schedule IV controlled substance for short-term insomnia treatment when difficulty falling asleep persists; no secure after-hours shipping or online service can legally dispense it without thorough medical evaluation, and prescription-free purchases constitute federal felony distribution under 21 U.S.C. § 841.

The 10mg immediate-release dose serves as maximum for men (women/elderly start 5mg) taken once nightly with 7-8 hours sleep opportunity, limited to 7-10 days max under 2025 DEA telemedicine (ends 12/31/2025), requiring HIPAA video with ISI>14 confirming DSM-5 insomnia, excluding OSA (STOP-BANG<3), depression (PHQ-9<10), SUD (DAST<2), and CBT-I failure—no "shipping" bypasses EPCS or post-2025 in-person mandates.

Imidazopyridine GABA-A Profile

α1-selective agonist (Ki 25nM), Tmax 1.6h, t½ 2.5h; women 5mg (AUC 30-50% higher); contraindications: sleep apnea, myasthenia, severe liver; black box: complex sleep behaviors (sleep-driving 0.1-1%), next-day impairment (4x crash risk 10mg women), dependence (15% high-dose)—discontinue on behaviors.

Compliance Protocol

1. ISI≥15 + sleep diary.

2. Video (PDMP/STOP<3).

3. Consent (10-20% behaviors).

4. EPCS #30 tabs men.

5. C-IV signature delivery.

6. Day 7 check (>30min SOL reduction).

AE Matrix

Overdose: flumazenil cautious; CYP3A4i x2 AUC.

Non-Pharmacologic Ladder

FAQ

Ambien 10mg no Rx legal? No—Schedule IV felony.
Women dose? 5mg max.